Growth, growth factors and diabetes

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Growth, growth factors and diabetes.

Type 1 diabetes mellitus (T1DM) and other chronic diseases in children are well known to adversely affect linear growth and pubertal development. In the years immediately following the introduction of insulin therapy, short stature was consistently reported in children with T1DM. However, over the past 50 years significant improvement in the prognosis for growth and final height in children wit...

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Growth and growth factors in diabetes mellitus.

Growth of 79 children with diabetes was analysed at diagnosis and again after one to 10.7 years of treatment with insulin. Both sexes were tall at onset, whereas at the last observation boys alone showed significant growth retardation. Height standard deviation score (SDS), however, showed no significant fall either in 32 subjects reassessed after five years of disease or in 18 subjects examine...

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Growth and Growth Factors

SOCS2 inactivation, which leads to growth hormone hypersensitivity and overgrowth, is selected as the mechanism of the year in this chapter. The second paper shows that PPAR plays a role in the growth of male mice. Under new paradigms, we learn that the disruption of a paternally expressed gene from the Gnas locus, XL s, is associated with poor postnatal growth, and we also discover a new molec...

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Growth and Growth Factors

This collection of articles aims to provide a wide spectrum of studies on the subject of growth and growth factors, particularly focusing on those with direct or potential clinical implications. Of course, given the limited number of papers to be selected, the choice of articles has been fully arbitrary and, inevitably, other equally valuable studies have been neglected. Among experimental stud...

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Blood Cell Growth Factors

  SUMMARY Growth factors or colony stimulating factors (CSFs)recently became the subject of headlines around the world. Many published articles in the last few years indicate that the CSFs can correct anemia and pancytopenia of the great majority of patients. Recombinant CSFs are available to the many scientific and therapeutic centers in the U.S.A, Europe and Japan these days. Erythrop oieti...

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ژورنال

عنوان ژورنال: European Journal of Endocrinology

سال: 2004

ISSN: 0804-4643,1479-683X

DOI: 10.1530/eje.0.151u109